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InvivoGen 中和单克隆抗体
13 人阅读发布时间：2026-01-13 11:00
靶向细胞因子或其受体的中和抗体是研究免疫调节和开发治疗策略的有力工具。InvivoGen提供多种高品质重组单克隆抗体(monoclonal antibody, mAb)，这些抗体源自引证详实的生物仿制药或自主研发的克隆产品。我们提供来源于人类或小鼠的细胞因子靶向和细胞因子受体靶向mAb。为保证最佳性能，每个批次均使用对应的报告细胞和重组细胞因子进行功能测试和验证。
主要特点
• 重组单克隆抗体
• 源自引证详实的生物仿制药或自主研发的
• 产自CHO细胞
• 经过验证的中和作用
• 验证无内毒素
• 提供InvivoFitTM级别，可用于小鼠体内研究
应 用
• 中和试验
• 检测和生物活性试验
• 筛选试验
 |
InvivoGen中和抗体有哪些形式？ | |
| 生物仿制药mAb 重组mAb，其特征是候选药物或治疗药物的可变区和恒定区。 修饰同型的生物仿制药mAb对原始同型进行了修饰的重组生物仿制药mAb。 |
自主研发的mAb 产自InvivoGen特有的杂交瘤的重组mAb。在没有可用的生物仿制药的情况下开发。 InvivoFitTM mAbs具有鼠源可变区和恒定区的高质量重组mAb，专门针对小鼠体内研究。 |
|
  产品 |
靶点物种 | 克隆 | 同型 | 货号 |
| 细胞因子抗体 | ||||
| Anti-hAPRIL-hIgG2 | Human | Sibeprenlimab biosimilar - CAS # 2382896-07-1 | Human IgG2 | hapril-mab2 |
| Anti-hBAFF-hIgG1 | Human | Belimumab biosimilar - CAS # 356547-88-1 | Human IgG1 | hbaff-mab1 |
| Anti-hCD40L-hIgG1 | Human | Frexalimab biosimilar - CAS #2515463-86-0 | Human IgG1 | h40l-mab1 |
| Anti-hIFN-α-hIgG1 | Human | Rontalizumab biosimilar - CAS #948570-30-7 | Human IgG1 | hifna-mab1 |
| Anti-hIFN-β-IgG | Human | Clone 10B10 | Mouse IgG2a | mabg2-hifnb-3 |
| Anti-hIFN-γ-hIgG1 | Human | Fontolizumab biosimilar - CAS #326859-36-3 | Human IgG1 | hifng-mab1 |
| Anti-hIL-1α-IgG1 | Human | Clone 7D4 | Human IgG1 | mabg-hil1a-3 |
| Anti-mIL-1α-mIgG1 | Mouse | Clone 6H7 | Mouse IgG1 | mil1a-mab9-02 |
| Anti-hIL-1β-IgG1 | Human | Clone 4H5 | Mouse IgG1 | mabg-hil1b-3 |
| Anti-mIL-1β-mIgG1 | Mouse | Clone 7E3 | Mouse IgG1 | mil1b-mab9-02 |
| Anti-mIL-2-mIgG1e3 | Mouse | Clone S4B6 | Mouse IgG1e3 (D265A) | mil2-mab15-02 |
| Anti-hIL-6-IgG | Human | Clone 3H3 | Mouse IgG1 | mabg-hil6-3 |
| Anti-mIL-6-mIgG1e3 | Mouse | Clone 10F9 | Mouse IgG1e3 (D265A) | mil6-mab15-02 |
| Anti-hIL-9-hIgG1 | Human | Enokizumab biosimilar - CAS #909875-08-7 | Human IgG1 | hil9-mab1 |
| Anti-hIL-10-hIgG1 | Human | Clone 20G2 | Human IgG1 | mab1-hil10 |
| Anti-hIL-12/IL-23-p40-hIgG1 |
Human | Ustekinumab biosimilar - CAS #815610-63-0 | Human IgG1 | hil12p40-mab1 |
| Anti-mIL-13-mIgG1 | Mouse | Clone 8H8 | Mouse IgG1 | mil13-mab9-02 |
| Anti-hIL-15-hIgG1 | Human | Ordesekimab biosimilar - CAS #879293-15-9 | Human IgG1 | hil15-mab1 |
| Anti-hIL-16-hIgG1 | Human | Clone 14.1 | Human IgG1 | hil16-mab1-02 |
| Anti-mIL-16-mIgG1e3 | Mouse | Clone 14.1 | Mouse IgG1e3 (D265A) | mil16-mab15-02 |
| Anti-hIL17A-hIgG1 | Human | Secukinumab biosimilar - CAS #1229022-83-6 | Human IgG1 | hil17a-mab1 |
| Anti-hIL-18-hIgG1-FES | Human | Camoteskimab biosimilar - CAS #2492472-82-7 | Human IgG1 (L242F/L243E/P339S) | hil18-mab16 |
| Anti-hIL-20-hIgG4 (S228P) | Human | Fletikumab biosimilar - CAS #1357158-22-5 | Human IgG4 (S228P) | hil20-mab14 |
| Anti-hIL-21-hIgG1 | Human | Avizakimab biosimilar - CAS #2229685-51-0 | Human IgG1 (M252Y/S254T/T256E) | hil21-mab1 |
| Anti-hIL-22-hIgG1 | Human | Fezakinumab biosimilar - CAS #1007106-86-6 | Human IgG1 | hil22-mab1 |
| Anti-hIL-25-hIgG1 | Human | Clone 15G10 | Human IgG1 | hil25-mab1 |
| Anti-hIL-28a-IgG | Human | Clone 21C3 | Mouse IgG1 | mabg-hil28a-3 |
| Anti-hIL-28b-IgG | Human | Clone 18F4 | Mouse IgG1 | mabg-hil28b-3 |
| Anti-mIL-28b-mIgG1 | Mouse | Clone 3C11 | Mouse IgG1 | mil28b-mab9-02 |
| Anti-hIL-29-mIgG1 | Human | Clone 6A11 | Mouse IgG1 | mab9-hil29 |
| Anti-hRANKL-hIgG2 | Human | Denosumab biosimilar - CAS #615258-40-7 | Human IgG2 (*) | hrankl-mab2 |
| Anti-hTGF-β-hIgG4 (S228P) | Human | Fresolimumab biosimilar - CAS #948564-73-6 | Human IgG4 (S228P) | htgfb-mab14 |
| Anti-hTL1A-hIgG1 | Human | Tulisokibart biosimilar - CAS #2648504-55-4 | Human IgG1 | htl1a-mab1 |
| Anti-hTNF-α-hIgG1 | Human | Adalimumab biosimilar - CAS #331731-18-1 | Human IgG1 (*) | htnfa-mab1 |
| Anti-hTSLP-hIgG2 | Human | Tezepelumab biosimilar - CAS #1572943-04-4 | Human IgG2 | htslp-mab2 |
| 细胞因子受体抗体 | ||||
| Anti-hEGFR-hIgG1 | Human | Cetuximab biosimilar - CAS #205923-56-4 | Human IgG1 | hegfr-mab1 |
| Anti-hGM-CSFR-hIgG4 (S228P) | Human | Mavrilimumab biosimilar - CAS #1085337-57-0 | Human IgG4 (S228P) | hgmcsfr-mab14 |
| Anti-hIFNAR-hIgG1-FES | Human | Anifrolumab biosimilar - CAS #1326232-46-5 | Human IgG1 (L242F/L243E/P339S) (*) | hifnar-mab16 |
| Anti-hIL1RAP-hIgG1 | Human | Nidanilimab biosimilar - CAS #2171061-85-9 | Human IgG1 | hil1rap-mab1 |
| Anti-hIL-3R-hIgG1-DE | Human | Talacotuzumab biosimilar - CAS #1826831-79-1 | Human IgG1 (S239D/I332E) | hil3r-mab18 |
| Anti-hIL-5R-hIgG1fut | Human | Benralizumab biosimilar - CAS #1044511-01-4 | Human IgG1 | hil5r-mab13 |
| Anti-hIL6R-To-hIgG1 | Human | Tocilizumab biosimilar - CAS #375823-41-9 | Human IgG1(*) | hil6rto-mab1 |
| Anti-hIL-31R-hIgG2 | Human | Nemolizumab biosimilar - CAS #1476039-58-3 | Human IgG2 | hil31r-mab2 |
| Anti-hIL-33R-hIgG2 | Human | Astegolimab biosimilar - CAS #2173054-79-8 | Human IgG2 | hil33r-mab2 |
| Anti-hIL-36R-hIgG4 (S228P) | Human | Imsidolimab biosimilar - CAS #2102543-86-0 | Human IgG4 (S228P) | hil36r-mab14 |
| 产品 | 克隆 | 同型 | 货号 |
| INVIVOFITTM MOUSE CYTOKINE ANTIBODIES | |||
| Anti-mIL-1α-mIgG1 InvivoFit™ | Clone 6H7 | Mouse IgG1 | mil1a-mab9-1 |
| Anti-mIL-1β-mIgG1 InvivoFit™ | Clone 7E3 | Mouse IgG1 | mil1b-mab9-1 |
| Anti-mIL-2-mIgG1e3 InvivoFit™ | Clone S4B6 | Mouse IgG1e3 (D265A) | mil2-mab15-1 |
| Anti-mIL-6-mIgG1e3 InvivoFit™ | Clone 10F9 | Mouse IgG1e3 (D265A) | mil6-mab15-1 |
| Anti-mIL-13-mIgG1 InvivoFit™ | Clone 8H8 | Mouse IgG1 | mil13-mab9-1 |
| Anti-mIL-16-mIgG1e3 InvivoFit™ | Clone 14.1 | Mouse IgG1e3 (D265A) | mil16-mab15-1 |
| Anti-mIL-28b-mIgG1 InvivoFit™ | Clone 3C11 | Mouse IgG1 | mil28b-mab9-1 |
| 相关产品 | 货号 |
| Cytokine Antagonist Screening Service | cytk-ant |
| Anti-β-Gal-hIgG1 (control*) | bgal-mab1 |
| Anti-β-Gal-mIgG1 InvivoFit™ (control*) | bgal-mab9-1 |
INVIVOFITTM GRADE
InvivoFit™是专为体内研究设计的高质量标准。InvivoFit™产品经0.2μm过滤除菌，并在严格的无菌条件下罐装。各批次产品的细菌污染物(内毒素和脂蛋白)水平均通过瘊试剂盒(LAL)检测以及TLR2和TLR4报告细胞检测进行验证。
(*) 多种同型可供选择，详情请联系我们的代理商欣博盛生物，或访问我们的网站。
更多详情请联系 InvivoGen 中国授权代理-欣博盛生物
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