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708 人阅读发布时间：2014-06-04 14:06

The Dengue virus (DEN) is of the genus Flavivirus and possesses a positive-strand RNA genome of approximately 10.6 kb that contains a single open-reading frame encoding for a polyprotein， which can be further cleaved by cellular and viral proteases into three structural proteins (capsid protein C, membrane protein M, envelope protein E), and seven non-structural proteins (NS 1, NS2a, NS2b, NS3, NS4a, NS4b, NS5). There are four serotypes (DEN 1-4), though there is certainly genotypic variability in individual viral genomes within each serotype. This variability is thought to have minimal clinical significance , as human infection from any of the four serotypes results in long-term immunity to that serotype . However, cross-immunity between serotypes is of much shorter duration , meaning that many people are victims of sequential infection by different serotypes. This is clinically very important, as sequential infection appears to be a risk factor for more serious disease manifestations.

Dengue Virus Protein Schematic Diagram (Non-Structural Proteins (Orange)

Dengue virus 1, 2, 3 & 4 antibody [D1-11 (3)] (GTX29202) NS1 (Dengue virus ) antibody [GT1 061] (GTX630SS7)

Dengue virus antibody detects Dengue virus 1 protein at NS1 antibody detects NS1 (Dengue virus) protein at

cytoplasm by immunofluorescent analysis cytoplasm by immunofluorescent analysis

Envelope protein (Dengue virus) antibody [GT214] (GTX629116) WB analysis for all blots

Envelope protein antibody detects Envelope protein (Dengue A: BHK-21; B: DEN2-infecled BHK-21; C: JEV-infecled BHK

virus) protein at cytoplasm by immunofluorescent analysis -21 Blols probed wilh Rb pAb 10 (Ieft 10 righl): NS1 (GTX124
280); NS2B (GTX124246); NS3 (GTX124252); NS4B (GTX124

250); NS5 (GTX124253)

Cat.NO	Product	Reactivity	Host&Clonality	Application
GTX29202	Dengue Virus 1, 2, 3 & 4 antibody [D1-11(3)]	DEN	Ms mAb IgG2a	Dot blot, ELlSA, ICC/IF, WB
GTX41428	Dengue Virus Type 2 antibody [NYRDeng2]	DEN2	Ms mAb IgG1	ELISA. WB
GTX43295	Dengue Types 1,2,3,4 antibody [BDI419]	DEN	Ms mAb IgG2a	Dot blot, ELlSA, ICC川F
GTX41437	Dengue Virus antibody [5161]	DEN	Ms mAb IgG2a	ELISA
GTX41430	Dengue Virus Type 2 antibody [3H5.1]	DEN2	Ms mAb IgG1	ICC/IF
GTX43296	Dengue Type 2, envelope antibody [B932M]	DEN2	Ms mAb IgG1	ICC/IF
GTX124247	Capsid Protein (Dengue Virus) antibody	Capsid (DEN)	Rb pAb	WB
GTX103343	Capsid Protein (Dengue Virus) antibody	Capsid (DEN)	Rb pAb	ICC/IF. WB
GTX128092	PrM (Dengue Virus) antibody	PrM (DEN)	Rb pAb	WB
GTX128093	PrM (Dengue Virus) antibody	PrM (DEN)	Rb pAb	WB
GTX127277	Envelope protein (Dengue Virus) antibody	Envelope (DEN)	Rb pAb	ICC/IF. WB
GTX629116	Envelope protein (Dengue Virus) antibody [GT214]	Envelope (DEN)	Ms mAb IgG2a	ICC/IF. WB
GTX629117	Envelope protein (Dengue Virus) antibody [GT643]	Envelope (DEN)	Ms mAb IgG2b	ICC/IF. WB
GTX630557	NS1 (Dengue virus) antibody [GT1061]	NS1 (DEN)	Ms mAb IgG1(NEW Producr)	ICC/IF. WB
GTX630556	NS1 (Dengue virus) antibody [GT4212]	NS1 (DEN)	Ms mAb IgG2a(NEW Producr)	ICC/IF. WB
GTX103346	NS1 (Dengue Virus 2) antibody	NS1 (DEN2)	Rb pAb	ICC/IF. WB
GTX124280	NS1 (Dengue Virus) antibody	NS1 (DEN)	Rb pAb	ICC/IF. WB
GTX124246	NS2B (Dengue Virus) antibody	NS2B (DEN)	Rb pAb	ICC/IF. WB
GTX124252	NS3 (Dengue Virus) antibody	NS3 (DEN)	Rb pAb	ICC/IF. WB
GTX629477	NS3 (Dengue Virus) antibody [GT2811]	NS3 (DEN)	Ms mAb IgG1	ICC/IF. WB
GTX124249	NS4A (Dengue Virus) antibody	NS4A (DEN)	Rb pAb	WB
GTX103349	NS4B (Dengue Virus) antibody	NS4B (DEN)	Rb pAb	ICC/IF. WB
GTX124250	NS4B (Dengue Virus) antibody	NS4B (DEN)	Rb pAb	ICC/IF. WB

流式细胞术——补偿微球篇

调节性T细胞(Treg)检测试剂盒

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