Trilink CleanCap® Reagent AG - (N-7113)产品介绍

Trilink CleanCap^® Reagent AG - (N-7113)产品介绍

mRNA共转录加帽产品CleanCap^® Reagent AG，m7G(5')ppp(5')(2'OMeA)pG

 

产品描述：

CleanCap^® Reagent AG是Trilink专利加帽产品，Trilink N-7113体外共转录，5’端加帽形成cap1结构。CleanCap的加帽效率可以达到98%。请注意：Trilink推荐尽可能使用CleanCapAG，CleanCap AG需要AG启动子。通常情况下，CleanCap AG的加帽效率>90%。和CleanCap AG不同，CleanCap GG (cat. no. N-7133 or N-7433) 的专利效率和产量和ARCA类似。

 

产品信息：

产品货号	N-7113
纯度	≥95% by AX-HPLC
消光系数	30,539 Lmol-1cm-1 at 255 nm
分子式	C32H43N15O24P4 (游离酸)
分子质量	1145.60 g/mole (游离酸)
盐形式	Na+
浓度	100 mM
溶液组分	水
推荐的储存温度	-20°C 或者以下
其他名称	CleanCap® Reagent AG for co-transcriptional capping of mRNA,m7G(5')ppp(5')(2'OMeA)pG
应用	CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases
主链	5'-5'-三磷酸
碱基类似物	腺苷酸，鸟苷酸
核苷酸种类	帽类似物

 

产品规格如下：

供应商	产品编号	产品名称	规格
TriLink	N-7113-1	CleanCap Reagent  AG,  1 umole	1 umol
TriLink	N-7113-10	CleanCap Reagent AG, 10 umoles	10 umol
TriLink	N-7113-100	CleanCap Reagent AG, 100 µmole	100 umol
TriLink	N-7113-5	CleanCap Reagent AG, 5 umole	5 umol

 

文献引用；

Jiang, T;Henderson, JM;Coote, K;Cheng, Y;Valley, HC;Zhang, XO;Wang, Q;Rhym, LH;Cao, Y;Newby, GA;Bihler, H;Mense, M;Weng, Z;Anderson, DG;McCaffrey, AP;Liu, DR;Xue, W; . Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

Tusup, M;L . mRNA-Based Anti-TCR CDR3 Tumour Vaccine for T-Cell Lymphoma

Yu, D;Kaur, G;Blumenthal, RM;Zhang, X;Cheng, X; . Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima

Dobie?y?ska, A;Miszkiewicz, J;Dar?ynkiewicz, ZM;Tyras, M;Stankiewicz-Drogo?, A;Trylska, J;Dar?ynkiewicz, E;Grzela, R; . Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies

Hashimoto, K;Kodama, A;Ohira, M;Kimoto, M;Nakagawa, R;Usui, Y;Ujihara, Y;Hanashima, A;Mohri, S; . Transient induction of cell cycle promoter Fam64a improves cardiac function through regulating Klf15-dependent cardiomyocyte differentiation in mice

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