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Funakoshi热销产品——肿瘤细胞迁移抑制剂——Migrastatin

发布时间:2020-02-20 11:47 |  点击次数:

肿瘤细胞迁移抑制剂——Migrastatin   


Migrastatin可抑制肿瘤细胞迁移,为抑制细胞转移提供一种手段



 
Application Notes
● Migrastatin抑制人食道癌细胞(EC17)小鼠黑色素瘤细胞(B16)迁移1).
● 有研究发现Migrastatin以抑制人小细胞肺癌细胞(Ms-1)的锚固-非依赖性生长2).
1) Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Nakae K, Yoshimoto Y, Sawa T, Homma Y, Hamada M, Takeuchi T, Imoto M. J. Antibiotics, 2000, 53, 1130-1136.
2) Migrastatin, a novel 14-membered ring macrolide, inhibits anchorage-independent growth of human small cell lung carcinoma Ms-1 cells. Takemoto Y, Nakae K, Kawatani M, Takahashi Y, Naganawa H, Imoto M. J. Antibiotics, 2001, 54, 1104-1107.


产品信息:
 

Coad No.:  10708
CAS#:  314245-65-3
Molecular Formula:  C27H39NO7
Molecular Weight:  489.609
Source:  Streptomyces sp. MK929-43F1
Appearance:  White powder
Purity:  > 90% (HPLC)
Long Term Storge:  at-20
Solubility:  Soluble in MeOH, DMSO, DMF.Insoluble in H2O
 
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