X连锁α-地中海贫血/精神发育迟滞(又叫ATR-X综合征)是一种X连锁遗传的精神发育迟滞综合征。大约有一半的患者已发现有ATRX基因突变。转录调节因子ATRX也称为ATP依赖性解旋酶ATRX。X连锁核蛋白(XNP)或X连锁解旋酶II是由ATRX编码的蛋白质。ATRX基因的突变与X连锁精神发育迟滞(XLMR)综合征相关,常伴有α-地中海贫血(ATRX)综合征。 产品详情: 类型:多克隆抗体 来源:Rabbit IgG 应用: IHC,WB,ICC-IF 反应种属:human 免疫原:Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRR 缓冲液组成:40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative
应用实例:
Immunohistochemical staining of human uterine cervix shows moderate to strong nuclear positivity in sequamous epithelial cells.
WB analysis in A549 cells transfected with control siRNA, target specific siRNA probe#1 and #2, using anti-ATRX antibody. Remaining relative intensity is presented. Loading control:anti-GAPDH.
mmunofluorescent staining of human cell line A549 shows localization to nucleoplasm and nuclear bodies. Antibody staining is shown in green.